Imaging-Guided Regenerative Aesthetics: A Review of PRP, Stem-Cell, and Fat-Derived Therapies in Interventional Radiology


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Article DOI: https://doi.org/10.64573/torgj2601001

Authors: Ishaan Bakshi1,4, Parikshta Sookrah2, Hriday Singh Rawat3,4, Prashant Anand3, Sakshi Singh3

1Dr. DY Patil University; Royal College of Radiologists
2Elevé Aesthetic Clinic, Mauritius
3Anna Medical College, University of Technology, Mauritius
4The Operating Room Global (TORG).

Cite:

  • APA (7th edition): Bakshi, I., Sookrah, P., Rawat, H. S., Anand, P., & Singh, S. (2026, January 28). Imaging-guided regenerative aesthetics: A review of PRP, stem-cell, and fat-derived therapies in interventional radiology. The Operating Room Global Journal (TORGJ), 2(1). https://doi.org/10.64573/torgj2601001
  • Harvard: Bakshi, I., Sookrah, P., Rawat, H.S., Anand, P. and Singh, S., 2026. Imaging-guided regenerative aesthetics: A review of PRP, stem-cell, and fat-derived therapies in interventional radiology. The Operating Room Global Journal (TORGJ), 2(1). Published 28 January. Available at: https://doi.org/10.64573/torgj2601001
  • Vancouver: Bakshi I, Sookrah P, Rawat HS, Anand P, Singh S. Imaging-guided regenerative aesthetics: A review of PRP, stem-cell, and fat-derived therapies in interventional radiology. The Operating Room Global Journal (TORGJ). 2026 Jan 28;2(1). https://doi.org/10.64573/torgj2601001
  • MLA (9th edition): Bakshi, Ishaan, et al. “Imaging-Guided Regenerative Aesthetics: A Review of PRP, Stem-Cell, and Fat-Derived Therapies in Interventional Radiology.” The Operating Room Global Journal (TORGJ), vol. 2, no. 1, 28 Jan. 2026, https://doi.org/10.64573/torgj2601001
  • Chicago (Author-Date): Bakshi, Ishaan, Parikshta Sookrah, Hriday Singh Rawat, Prashant Anand, and Sakshi Singh. 2026. “Imaging-Guided Regenerative Aesthetics: A Review of PRP, Stem-Cell, and Fat-Derived Therapies in Interventional Radiology.” The Operating Room Global Journal (TORGJ) 2 (1), January 28. https://doi.org/10.64573/torgj2601001
ABSTRACT
Background: The regenerative field of aesthetic medicine has placed a growing emphasis on using biologically derived, minimally invasive techniques through which tissue function and quality can be restored. Autologous (patient’s own) therapies such as platelet-rich plasma (PRP), stem-cell-derived products, and fat-derived grafts have become common treatments for a variety of indications including facial rejuvenation, scar treatment, and hair restoration. Most of these treatments are currently performed with the aid of landmark-based methods for injecting, which can lead to inconsistent results and increased risks during procedures.
Rationale and Purpose: Interventional radiology offers the opportunity to use a more precise image-guided technique with the use of real-time imaging (i.e., ultrasound) to view vascular structures and soft-tissue planes as they are placed within the body. This allows for better needle placement and allows for the accurate delivery of biologic agents with significantly less risk of intravascular injections. The purpose of this narrative review is to describe the current body of literature regarding the use of imaging guidance to aid in the delivery of regenerative aesthetic medical procedures. It will address the following components: clinical efficacy, safety, regulatory aspects, and standardization of the imaging technique.
Methods and Results: A structured search of the literature was completed using PubMed, Embase, and the Cochrane Database from 2020 to July 2025.Based on the available studies, image-guided delivery of biologic medications does demonstrate an increase in procedural accuracy, improves the distribution of grafts within tissues, and leads to improved patient-reported outcomes when compared to traditional methods of injection. However, much variation exists in the methods of biologic preparation, methods to assess the outcomes, and length of time patients are followed the procedure.
Conclusion: Recent evidence has shown that imaging guidance can help increase both safety and reproducibility in various areas of the patient care continuum. However, there continues to be a lack of high-quality randomized trials demonstrating the benefits associated with imaging guidance and comprehensive standardized protocols for the utilisation of imaging guidance, which ultimately hampers the development of clinically significant evidence-based treatment algorithms. A need for additional multi-disciplinary studies is present to create valid and scientifically based guidelines for incorporating the use of interventional radiology within regenerative aesthetic practices.
Keywords: Platelet-rich plasma; stem-cell therapy; fat grafting; regenerative aesthetics; interventional radiology; ultrasound-guided injection; imaging guidance.

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