Early Postoperative Recovery Outcomes of Minimally Invasive Versus Conventional Cardiac Surgery in Adult Patients in Pakistan: A Retrospective Cohort Study

The Operating Room Global Journal · Volume 2 · Issue 3 · September 2026
Original Research · Cardiac Surgery · Retrospective Cohort Study

Early Postoperative Recovery Outcomes of Minimally Invasive Versus Conventional Cardiac Surgery in Adult Patients in Pakistan: A Retrospective Cohort Study

Fatima Jaweria1,6*, Myada A. Ibrahim2,6, Zia Un Nisa3, Saman Aziz4, Muhammad Muzammil Ramzan5
JournalThe Operating Room Global Journal
Volume / IssueVolume 2 · Issue 3
Article TypeOriginal Research
Available Online25 September 2026
Article DOI10.64573/torgj2608007
Author & Affiliation

Authors

Fatima Jaweria1,6*, Myada A. Ibrahim2,6, Zia Un Nisa3, Saman Aziz4, Muhammad Muzammil Ramzan5

1 Ibadat International University, Islamabad, Pakistan
2 University of Global Health Equity (UGHE), Rwanda
3 National Institute of Health, Islamabad, Pakistan
4 Riphah International University, Islamabad, Pakistan
5 Farooq Teaching Hospital
6 The Operating Room Global (TORG)

Corresponding Author: Fatima Jaweria · [email protected]

Abstract

Study Summary

Background

Cardiac surgery is indicated when medical therapy fails to control myocardial ischemia, ventricular dysfunction, or hemodynamic instability. Conventional full sternotomy carries substantial perioperative trauma, while minimally invasive cardiac surgery (MICS) aims to reduce access-related morbidity, though evidence from Pakistan remains limited. This study compared early postoperative recovery and examined factors associated with prolonged ventilation and short intensive care unit (ICU) stay after MICS versus conventional surgery.

Methods

In this retrospective cohort study, records of 98 adults (49 conventional, 49 MICS) undergoing coronary or valvular surgery at a single tertiary center in Pakistan between November 2025 and May 2026 were analyzed using the Mann–Whitney U test, chi-square or Fisher’s exact test, and multivariable binary logistic regression.

Results

MICS was associated with significantly shorter ventilation time, shorter ICU stay, and lower intra-aortic balloon pump (IABP) use (6.1% vs 22.4%; p=0.040). Inotropic support and re-exploration favored MICS without reaching conventional statistical significance. Surgical approach was the only independent predictor of short ICU stay (AOR 7.47, 95% CI 2.28–24.55, p=0.001) and approached significance for prolonged ventilation (AOR 8.59, 95% CI 1.00–73.88, p=0.050).

Conclusion

MICS was associated with faster early recovery than conventional surgery in this Pakistani cohort, despite higher BMI and longer operative time. Given the retrospective design, these findings reflect association rather than causation and support prospective evaluation of MICS in Pakistani tertiary centers.

Keywords: Minimally Invasive Surgical Procedures · Cardiac Surgical Procedures · Postoperative Care · Intensive Care Units · Intra-Aortic Balloon Pumping

Early Recovery

Postoperative Outcomes at a Glance

98Adults included in the cohort
49 / 49Conventional surgery / MICS
p<0.001Ventilation time · shorter with MICS
p<0.001ICU stay · shorter with MICS
Interpretation: MICS was associated with faster early postoperative recovery, with large between-group effects reported for ventilation time (r=0.42) and ICU stay (r=0.65).
Support & Re-Exploration

Postoperative Support Requirements

6.1%IABP use after MICS
22.4%IABP use after conventional surgery
22.4%Inotropic support after MICS vs 40.8% conventional
8.2%Re-exploration after MICS vs 22.4% conventional
Statistical context: IABP use was significantly lower after MICS (Fisher’s exact p=0.040). Inotropic support (p=0.051) and re-exploration (p=0.090) showed directionally favorable differences without reaching conventional statistical significance.
Adjusted Analysis

Predictors of Early Recovery

AOR 7.47Conventional vs MICS · short ICU stay model
2.28–24.5595% CI · short ICU stay
AOR 8.59Conventional vs MICS · prolonged ventilation model
1.00–73.8895% CI · prolonged ventilation
Model interpretation: Surgical approach was the only significant independent predictor in the short ICU stay model (p=0.001). The prolonged ventilation estimate was imprecise and approached significance (p=0.050), while the overall prolonged-ventilation model was not statistically significant.
Methods

Study Design & Analytical Approach

A quantitative retrospective cohort study comparing early postoperative recovery following minimally invasive and conventional cardiac surgery at a single tertiary-care cardiac center in Pakistan.

Study Period

November 2025–May 2026

Participants

Adults undergoing CABG or valve surgery.

Sampling

Quota-based consecutive sampling to 49 patients per group.

Analysis

SPSS 26; t-test/Mann–Whitney U, chi-square/Fisher’s exact test, and binary logistic regression.

Analytical caution: The retrospective, non-randomized, single-center design limits control of confounding and does not establish causation. The sample was powered for the primary continuous recovery outcome and may have been underpowered for lower-frequency binary outcomes.
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Cite This Article

Citation Generator

Jaweria F, Ibrahim MA, Nisa ZU, Aziz S, Ramzan MM. Early postoperative recovery outcomes of minimally invasive versus conventional cardiac surgery in adult patients in Pakistan: a retrospective cohort study. The Operating Room Global Journal (TORGJ). 2026 Sep 25;2(3). https://doi.org/10.64573/torgj2608007
Publication Information

Article Details

Article Type

Original Research

Retrospective cohort study of early postoperative cardiac-surgery recovery.

Article History

Editorial Timeline

Received 26 August 2026
Accepted 19 September 2026
Available Online 25 September 2026

Corresponding Author

Fatima Jaweria

[email protected]

Open Access

CC BY 4.0

Creative Commons Attribution 4.0 International licence.

Declarations

Conflict & Funding

No conflicts of interest. No specific funding; conducted under the TORG Global Research Fellowship (Mentorship Track).

Journal Record

Volume 2 · Issue 3

September 2026 · ISSN 3105-3262
DOI: 10.64573/torgj2608007

Ethical Approval

TORG-IRB

Approval reference TORG-IRB/2026/032501; protocol ID TORG-IRB-20260325-01; approved 6 May 2026. Retrospective medical-record abstraction began after approval.

AI Use Declaration

Drafting & Formatting Support

Claude (Anthropic) was declared for drafting, restructuring, formatting and reference-list reformatting from the authors’ original dissertation data and analysis. It was not used to collect, generate, analyze or interpret study data or results.

Study Setting

Pakistan

Single high-volume tertiary-care cardiac center with conventional and minimally invasive cardiac surgical services.

Contributor Roles

Author Contributions (CRediT)

Fatima Jaweria: Project administration, Conceptualization, Methodology, Data curation, Formal analysis, Investigation, Writing – original draft.

Myada A. Ibrahim: Supervision, review and editing. Zia Un Nisa: Writing, review and editing. Saman Aziz: Writing, review and editing. Muhammad Muzammil Ramzan: Writing, review and editing.

All authors approved the final manuscript and take responsibility for the integrity of the work.